Dogs with short coats require virtually no grooming, just a brush and wipe down every so often. Pet dogs with long coats require either regular clipping every eight weeks or so (where their coats are clipped short) or there long coats need to be brushed practically every day. Show dogs, or dogs with long coats, require daily brushing or else there coat will become matted and tangled. Not only can it hurt your dog if he has tangled and matted hair, but it will also become dirty and he will look shaggy and ugly if you do not regularly brush his coat.
Keep in mind that large dogs are more expensive to keep. They eat more food, which costs you more money. Tick and flea preventives cost more for large dogs, as do other mediations.
Some breeds have so much energy and are so active that if you do not give them a sufficient workout every day - a long walk and hard run - their pent up energy will quite likely manifest itself in destructive behavior.
You do not have to have own a large house to own a large dog (although a tiny apartment is not going to be big enough for one of the giant breeds). If you can take him outside for a good hour of two of exercise every day... a large dog can live in a small house or apartment just fine.
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