When large dogs eliminate, they eliminate a lot more than small dogs. More goes in and more comes out of large breeds. Which is something to keep in mind if your dog will live inside - especially if you live in a high rise apartment and he will have to be litter box trained (there is always going to be more to clean up).
Today there are over 400 recognized breeds of dogs in the world. Many of them have historical origins dating back hundreds, even thousands of years. Wherever humans have lived, dogs have been alongside them performing various tasks. One of the reasons dogs have been such a successful species is because they are so adaptable. They have made themselves useful in countless ways to humans so we kept feeding them, providing shelter for them, and, yes, breeding them. It’s no accident that we have dogs able to hunt, herd, guard, track, and do so many other things at an expert level. Humans figured out early on that if you bred dogs that were good at these things, you would get offspring that were also good at doing them. All of these jobs performed by dogs were necessary for our own species to survive. It’s no secret that we owe a lot to dogs, just as we do to other animals.
Though groups like the American Kennel Club make very specific designations about breeds and breed hybrids, there continue to be new breeds and breed variants developed all the time, as well as "up and coming breeds" not officially recognized by kennel clubs and experts. (Many dogs not purchased directly from breeders are also mixed-breeds of some kind, or have less than purebred ancestry.)
Every breed can be trained to learn almost every command. However, some breeds learn a lot faster than others - making them a lot easier to train. These highly intelligent breeds pick up a command after only about five or six repetitions, they more often respond on the first time you give the command, and they remember commands even if they are not practiced often. They also learn commands even when the trainer is inexperienced and makes mistakes. So if you do not have a lot of the time to spend dog training, or you are the impatient type who gets frustrated easily, choose a breed which has a high ease of training rating.