Some dogs will patiently put up with little children who pull their ears or accidentally poke them in the eyes, while others will not and map nip or bite back in defense. So if you want a dog who is excellent with children avoid breeds which may have a dominance streak or that have short tempers.
Most all dogs will get along well with children if they are raised with them. However, some breeds have a protective streak in them and may become aggressive with children who get to close at meal time (although this should not be tolerated), or aggressive with children they have never met. These breeds will likely see the children as being underneath themselves in the "pack order" and may try to dominate them.
When large dogs eliminate, they eliminate a lot more than small dogs. More goes in and more comes out of large breeds. Which is something to keep in mind if your dog will live inside - especially if you live in a high rise apartment and he will have to be litter box trained (there is always going to be more to clean up).
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