When large dogs eliminate, they eliminate a lot more than small dogs. More goes in and more comes out of large breeds. Which is something to keep in mind if your dog will live inside - especially if you live in a high rise apartment and he will have to be litter box trained (there is always going to be more to clean up).
Dog breeds are typically divided into a few basic categories: companion dogs, guard dogs, hunting dogs, herding dogs and working dogs. The top dog breeds for every purpose are represented here. Despite the names, in contemporary America, most breeds - even hunting or herding dogs - service as companies for individuals and families.
If you do not like loose dog hair and do not want to be vacuuming the house every day, then do not buy a high shedding breed. If you own a high shedding dog you will find hair everywhere! Including on your clothes, on your furniture, in your bed, and even in your food. Additionally dogs that have a high shedding rate need to be brushed more often to brush out the dead hair.
Keep in mind that large dogs are more expensive to keep. They eat more food, which costs you more money. Tick and flea preventives cost more for large dogs, as do other mediations.